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LIN28A Rabbit pAb

Anti-LIN28A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213823

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213823
Product Name:   Anti-LIN28A Rabbit Polyclonal Antibody
Synonyms:   CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
UNIPROT ID:   Q9H9Z2 (Gene Accession – NP_078950 )
Background:    This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
Immunogen:    Synthetic peptide of human LIN28A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 213823(LIN28A Antibody) at a dilution of 1/15(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 213823(Anti-LIN28A Antibody) at dilution 1/15.
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