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LINGO1 Rabbit pAb

Anti-LINGO1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221456

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221456
Product Name:   Anti-LINGO1 Rabbit Polyclonal Antibody
Synonyms:   LERN1; MRT64; LRRN6A; UNQ201
UNIPROT ID:   Q96FE5 (Gene Accession – NP_116197 )
Background:    Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).
Immunogen:    Synthetic peptide of human LINGO1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221456(LINGO1 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221456(Anti-LINGO1 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 221456(Anti-LINGO1 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D263052(Anti-LINGO1 Antibody) at dilution 1/50.
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