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LRP1 Rabbit mAb

Anti-LRP1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261644

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261644
Product Name:   Anti-LRP1 Rabbit Monoclonal Antibody
Synonyms:   A2MR; alpha 2MR; Alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5
UNIPROT ID:   Q07954
Background:    Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
Immunogen:    A synthetic peptide of human LRP1
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-4E8
MW:    Calculated MW: 505 kDa; Observed MW: 85 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of LRP1 in rat Brain, C6 lysates using LRP1 antibody

Immunocytochemistry analysis of LRP1 (green) in U87-MG using LRP1 antibody,and DAPI(blue).

Western blot analysis of LRP1 in mouse brain lysates using LRP1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using LRP1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications