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LRRK2 Rabbit pAb

Anti-LRRK2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216622

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216622
Product Name:   Anti-LRRK2 Rabbit Polyclonal Antibody
Synonyms:   PARK8; RIPK7; ROCO2; AURA17; DARDARIN
UNIPROT ID:   Q5S007 (Gene Accession – BC117180 )
Background:    This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Immunogen:    Fusion protein of human LRRK2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216622(LRRK2 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216622(Anti-LRRK2 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216622(Anti-LRRK2 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D220934(Anti-LRRK2 Antibody) at dilution 1/30.
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