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MACC1 Rabbit pAb

Anti-MACC1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220685

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220685
Product Name:   Anti-MACC1 Rabbit Polyclonal Antibody
Synonyms:   7A5; SH3BP4L
UNIPROT ID:   Q6ZN28 (Gene Accession – NP_877439 )
Background:    MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival
Immunogen:    Synthetic peptide of human MACC1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220685(MACC1 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220685(Anti-MACC1 Antibody) at dilution 1/35.
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