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MAGEA11 Rabbit pAb

Anti-MAGEA11 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220687

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220687
Product Name:   Anti-MAGEA11 Rabbit Polyclonal Antibody
Synonyms:   CT1.11; MAGE11; MAGE-11; MAGEA-11
UNIPROT ID:   P43364 (Gene Accession – NP_001011544 )
Background:    This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human MAGEA11
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220687(MAGEA11 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220687(Anti-MAGEA11 Antibody) at dilution 1/35.
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