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MAGEA8 Rabbit pAb

Anti-MAGEA8 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217588

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217588
Product Name:   Anti-MAGEA8 Rabbit Polyclonal Antibody
Synonyms:   CT1.8; MAGE8
UNIPROT ID:   P43361 (Gene Accession – BC002455 )
Background:    This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen:    Fusion protein of human MAGEA8
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217588(MAGEA8 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217588(Anti-MAGEA8 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 217588(Anti-MAGEA8 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D222646(Anti-MAGEA8 Antibody) at dilution 1/70.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: 293T cell lysate;
Primary antibody: 217588(MAGEA8 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 5 minutes
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