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MAP2K6 Rabbit pAb

Anti-MAP2K6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216632

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216632
Product Name:   Anti-MAP2K6 Rabbit Polyclonal Antibody
Synonyms:   MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, SAPKK-3
UNIPROT ID:   P52564 (Gene Accession – BC012009 )
Background:    This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Immunogen:    Fusion protein of human MAP2K6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216632(MAP2K6 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216632(Anti-MAP2K6 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 216632(Anti-MAP2K6 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D220950(Anti-MAP2K6 Antibody) at dilution 1/20.
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