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MAP3K20 Rabbit pAb

Anti-MAP3K20 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213309

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213309
Product Name:   Anti-MAP3K20 Rabbit Polyclonal Antibody
Synonyms:   pk; AZK; MLT; MRK; ZAK; CNM6; MLK7; MLTK; SFMMP; mlklak; MLTKbeta; MLTKalpha
UNIPROT ID:   Q9NYL2 (Gene Accession – NP_057737 )
Background:    This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Immunogen:    Synthetic peptide of human MAP3K20
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213309(MAP3K20 Antibody) at a dilution of 1/100(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213309(Anti-MAP3K20 Antibody) at dilution 1/100.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 213309(Anti-MAP3K20 Antibody) at a dilution of 1/100.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D156005(Anti-MAP3K20 Antibody) at dilution 1/100.
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