Email: info@neweastbio.com   |  Call: 6109452007

MAP4K3 Rabbit pAb

Anti-MAP4K3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216827

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216827
Product Name:   Anti-MAP4K3 Rabbit Polyclonal Antibody
Synonyms:   GLK; MEKKK3; MEKKK 3; MAPKKKK3; RAB8IPL1
UNIPROT ID:   Q8IVH8 (Gene Accession – BC071579 )
Background:    This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.
Immunogen:    Fusion protein of human MAP4K3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 216827(MAP4K3 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 216827(Anti-MAP4K3 Antibody) at dilution 1/30.

Gel: 10%SDS-PAGE, Lysate: 50 μg;
Lane: Mouse heart tissue;
Primary antibody: 216827(MAP4K3 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
          Publications