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MAPT Rabbit pAb

Anti-MAPT Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216821

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216821
Product Name:   Anti-MAPT Rabbit Polyclonal Antibody
Synonyms:   TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103
UNIPROT ID:   P10636 (Gene Accession – BC114948 )
Background:    This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes comple,x regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer’s disease, Pick’s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Immunogen:    Fusion protein of human MAPT
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 216821(MAPT Antibody) at a dilution of 1/75(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 216821(Anti-MAPT Antibody) at dilution 1/75.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse fetal brain tissue lysate;
Primary antibody: 216821(MAPT Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 5 seconds
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