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MBTPS2 Rabbit pAb

Anti-MBTPS2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222262

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222262
Product Name:   Anti-MBTPS2 Rabbit Polyclonal Antibody
Synonyms:   S2P; IFAP; KFSD; KFSDX; OLMSX; BRESEK
UNIPROT ID:   O43462 (Gene Accession – NP_056968 )
Background:    This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
Immunogen:    Synthetic peptide of human MBTPS2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: Oct-50;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cell Biology, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 222262(MBTPS2 Antibody) at a dilution of 1/30(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 222262(Anti-MBTPS2 Antibody) at dilution 1/30.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: RAW264.7 cell lysate;
Primary antibody: 222262(MBTPS2 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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