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MED28 Rabbit pAb

Anti-MED28 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218818

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218818
Product Name:   Anti-MED28 Rabbit Polyclonal Antibody
Synonyms:   EG1; magicin; 1500003D12Rik
UNIPROT ID:   Q9H204 (Gene Accession – BC011936 )
Background:    Component of the Mediator comple,x a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.
Immunogen:    Fusion protein of human MED28
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 200-400; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218818(MED28 Antibody) at a dilution of 1/200(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218818(Anti-MED28 Antibody) at dilution 1/200.
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