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MEIOB Rabbit pAb

Anti-MEIOB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218390

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218390
Product Name:   Anti-MEIOB Rabbit Polyclonal Antibody
Synonyms:   gs129; C16orf73
UNIPROT ID:   Q8N635 (Gene Accession – BC029829 )
Background:    Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3′-5′ exonuclease activity in vitro (By similarity).
Immunogen:    Fusion protein of human MEIOB
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218390(MEIOB Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218390(Anti-MEIOB Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 218390(Anti-MEIOB Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D224317(Anti-MEIOB Antibody) at dilution 1/30.
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