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MEKK2 Rabbit mAb

Anti-MEKK2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262508

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262508
Product Name:   Anti-MEKK2 Rabbit Monoclonal Antibody
Synonyms:   MAP3K2; MAPKKK2; MEKK2; Mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2
UNIPROT ID:   Q9Y2U5
Background:    The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates the kinases involved in the MAP kinase signaling pathway including MAPK7 and MAP2K4. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases (IKKs), and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2 (PRKCL2/PRK2), which suggests its involvement in PRKCL2 regulated signaling process.
Immunogen:    A synthetic peptide of human MEKK2
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-2K7
MW:    Calculated MW: 70 kDa; Observed MW: 70 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of MEKK2(green) in Hela using MEKK2 antibody,and DAPI(blue)

Western blot analysis of MEKK2 in C6, 3T3, Hela lysates using MEKK2 antibody.
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