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MMP1 Rabbit pAb

Anti-MMP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216266

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216266
Product Name:   Anti-MMP1 Rabbit Polyclonal Antibody
Synonyms:   CLG; CLGN
UNIPROT ID:   P03956 (Gene Accession – BC013875 )
Background:    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human MMP1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Cancer, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216266(MMP1 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216266(Anti-MMP1 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 216266(Anti-MMP1 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D220093(Anti-MMP1 Antibody) at dilution 1/60.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-6: Raji, Hepg2, A431, 293T, Jurkat and A375 cell lysates;
Primary antibody: 216266(MMP1 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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