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MMP10 Rabbit pAb

Anti-MMP10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219921

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219921
Product Name:   Anti-MMP10 Rabbit Polyclonal Antibody
Synonyms:   SL-2, STMY2
UNIPROT ID:   P09238 (Gene Accession – NP_002416 )
Background:    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Immunogen:    Synthetic peptide of human MMP10
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 15-50;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 219921(MMP10 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 219921(Anti-MMP10 Antibody) at dilution 1/15.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: NIH/3T3 cells;
Primary antibody: 219921(MMP10 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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