Email: info@neweastbio.com   |  Call: 6109452007

MRGPRX1 Rabbit pAb

Anti-MRGPRX1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220722

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220722
Product Name:   Anti-MRGPRX1 Rabbit Polyclonal Antibody
Synonyms:   GPCR; MGRG2; MRGX1; SNSR4
UNIPROT ID:   Q96LB2 (Gene Accession – NP_671732 )
Background:    MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.
Immunogen:    Synthetic peptide of human MRGPRX1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220722(MRGPRX1 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220722(Anti-MRGPRX1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 220722(Anti-MRGPRX1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D261921(Anti-MRGPRX1 Antibody) at dilution 1/40.
          Publications