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MRPL48 Rabbit pAb

Anti-MRPL48 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218837

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218837
Product Name:   Anti-MRPL48 Rabbit Polyclonal Antibody
Synonyms:   L48MT; CGI-118; HSPC290; MRP-L48
UNIPROT ID:   Q96GC5 (Gene Accession – BC009764 )
Background:    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.
Immunogen:    Fusion protein of human MRPL48
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 150-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 218837(MRPL48 Antibody) at a dilution of 1/150(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 218837(Anti-MRPL48 Antibody) at dilution 1/150.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 218837(Anti-MRPL48 Antibody) at a dilution of 1/150.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D225321(Anti-MRPL48 Antibody) at dilution 1/150.
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