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MT-ND6 Rabbit pAb

Anti-MT-ND6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220725

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220725
Product Name:   Anti-MT-ND6 Rabbit Polyclonal Antibody
Synonyms:   MTND6; ND6
UNIPROT ID:   P03923 (Gene Accession – YP_003024037 )
Background:    NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. The significance of NADH dehydrogenase subunit 6 (ND6) is rapidly becoming increasingly apparent as many mutations leading to amino acid changes in this subunit are associated with known mitochondrial diseases.
Immunogen:    Synthetic peptide of human MT-ND6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cancer, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220725(MT-ND6 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220725(Anti-MT-ND6 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 220725(Anti-MT-ND6 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D261927(Anti-MT-ND6 Antibody) at dilution 1/40.
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