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MTHFR Rabbit pAb

Anti-MTHFR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221503

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221503
Product Name:   Anti-MTHFR Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   P42898 (Gene Accession – NP_005948 )
Background:    The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Immunogen:    Synthetic peptide of human MTHFR
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221503(MTHFR Antibody) at a dilution of 1/35(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221503(Anti-MTHFR Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 221503(Anti-MTHFR Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D263129(Anti-MTHFR Antibody) at dilution 1/35.
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