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MUC20 Rabbit pAb

Anti-MUC20 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216661

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216661
Product Name:   Anti-MUC20 Rabbit Polyclonal Antibody
Synonyms:   MUC-20
UNIPROT ID:   Q8N307 (Gene Accession – BC029267 )
Background:    This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human MUC20
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216661(MUC20 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216661(Anti-MUC20 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 216661(Anti-MUC20 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D221008(Anti-MUC20 Antibody) at dilution 1/40.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse eyes tissue;
Primary antibody: 216661(MUC20 Antibody) at dilution 1/1400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 90 seconds
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