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MUC4 Rabbit pAb

Anti-MUC4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216101

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216101
Product Name:   Anti-MUC4 Rabbit Polyclonal Antibody
Synonyms:   ASGP; MUC-4; HSA276359
UNIPROT ID:   Q99102 (Gene Accession – NP_004523 )
Background:    The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervi,x are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.
Immunogen:    Synthetic peptide of human MUC4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 216101(MUC4 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 216101(Anti-MUC4 Antibody) at dilution 1/40.
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