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MYLK3 Rabbit pAb

Anti-MYLK3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217123

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217123
Product Name:   Anti-MYLK3 Rabbit Polyclonal Antibody
Synonyms:   MLCK; MLCK2; caMLCK
UNIPROT ID:   Q32MK0 (Gene Accession – BC109097 )
Background:    YLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
Immunogen:    Fusion protein of human MYLK3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217123(MYLK3 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217123(Anti-MYLK3 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 217123(Anti-MYLK3 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D221832(Anti-MYLK3 Antibody) at dilution 1/30.
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