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NCR2 Rabbit pAb

Anti-NCR2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220436

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220436
Product Name:   Anti-NCR2 Rabbit Polyclonal Antibody
Synonyms:   LY95; CD336; NKP44; NK-p44; dJ149M18.1
UNIPROT ID:   O95944 (Gene Accession – NP_001186438 )
Background:    Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336 (cluster of differentiation 336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.
Immunogen:    Synthetic peptide of human NCR2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220436(NCR2 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220436(Anti-NCR2 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220436(Anti-NCR2 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261527(Anti-NCR2 Antibody) at dilution 1/60.
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