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NDRG1 Rabbit pAb

Anti-NDRG1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220133

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220133
Product Name:   Anti-NDRG1 Rabbit Polyclonal Antibody
Synonyms:   GC4, RTP, DRG1, NDR1, NMSL, TDD5, CAP43, CMT4D, DRG-1, HMSNL, RIT42, TARG1, PROXY1
UNIPROT ID:   Q92597 (Gene Accession – NP_006087 )
Background:    This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen:    Synthetic peptide of human NDRG1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cardiovascular, Cancer, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220133(NDRG1 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220133(Anti-NDRG1 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 220133(Anti-NDRG1 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D261013(Anti-NDRG1 Antibody) at dilution 1/70.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: Human lymphoma tissue;
Primary antibody: 220133(NDRG1 Antibody) at dilution 1/1000;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 minutes
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