NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S211803 | ||||||
Product Name: Anti-NDUFB11 Rabbit Polyclonal Antibody | ||||||
Synonyms: ESSS; Np15; P17.3; NP17.3; CI-ESSS; LSDMCA3 | ||||||
UNIPROT ID: Q9NX14 (Gene Accession – BC010665 ) | ||||||
Background: Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity. | ||||||
Immunogen: Full length fusion protein | ||||||
Applications: ELISA, WB, IHC | ||||||
Recommended Dilutions: IHC: 50-300;WB: 1000-5000;ELISA: 5000-10000 | ||||||
Host Species: Rabbit | ||||||
Clonality: Rabbit Polyclonal | ||||||
Isotype: Immunogen-specific rabbit IgG | ||||||
Purification: Antigen affinity purification | ||||||
Species Reactivity: Human, Mouse | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
Research Areas: Metabolism, Cancer | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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