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NFYA Rabbit pAb

Anti-NFYA Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219326

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219326
Product Name:   Anti-NFYA Rabbit Polyclonal Antibody
Synonyms:   HAP2; CBF-A; CBF-B; NF-YA
UNIPROT ID:   P23511 (Gene Accession – BC039244 )
Background:    The protein encoded by this gene is one subunit of a trimeric comple,x forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Immunogen:    Fusion protein of human NFYA
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219326(NFYA Antibody) at a dilution of 1/80(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 219326(Anti-NFYA Antibody) at dilution 1/80.
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