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NLRP1 Rabbit pAb

Anti-NLRP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221248

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221248
Product Name:   Anti-NLRP1 Rabbit Polyclonal Antibody
Synonyms:   NAC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S
UNIPROT ID:   Q9C000 (Gene Accession – NP_127497 )
Background:    This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Immunogen:    Synthetic peptide of human NLRP1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221248(NLRP1 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221248(Anti-NLRP1 Antibody) at dilution 1/20.
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