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NLRP12 Rabbit pAb

Anti-NLRP12 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213221

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213221
Product Name:   Anti-NLRP12 Rabbit Polyclonal Antibody
Synonyms:   RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3
UNIPROT ID:   P59046 (Gene Accession – BC028069 )
Background:    This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human NLRP12
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 213221(NLRP12 Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 213221(Anti-NLRP12 Antibody) at dilution 1/80.
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