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NLRP6 Rabbit pAb

Anti-NLRP6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220732

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220732
Product Name:   Anti-NLRP6 Rabbit Polyclonal Antibody
Synonyms:   AVR; NAVR; PAN3; NALP6; PYPAF5; CLR11.4; NAVR/AVR
UNIPROT ID:   P59044 (Gene Accession – NP_612202 )
Background:    The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human NLRP6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220732(NLRP6 Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220732(Anti-NLRP6 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220732(Anti-NLRP6 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261937(Anti-NLRP6 Antibody) at dilution 1/40.
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