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NR3C1 Rabbit pAb

Anti-NR3C1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219828

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219828
Product Name:   Anti-NR3C1 Rabbit Polyclonal Antibody
Synonyms:   GR; GCR; GRL; GCCR
UNIPROT ID:   P04150 (Gene Accession – NP_000167 )
Background:    This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance.
Immunogen:    Synthetic peptide of human NR3C1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 219828(NR3C1 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 219828(Anti-NR3C1 Antibody) at dilution 1/50.
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