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NTH1 Rabbit mAb

Anti-NTH1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262626

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262626
Product Name:   Anti-NTH1 Rabbit Monoclonal Antibody
Synonyms:   FAP3; NTH1; OCTS3; hNTH1
UNIPROT ID:   P78549
Background:    Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3′ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
Immunogen:    Recombinant protein of human NTH1
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-8E9
MW:    Calculated MW: 34 kDa; Observed MW: 34 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of NTH1 in K562, Hela lysates using NTH1 antibody.

Immunocytochemistry analysis of NTH1 (green) in Hela using NTH1 antibody,and DAPI(blue).
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