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NUMA1 Rabbit pAb

Anti-NUMA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222374

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222374
Product Name:   Anti-NUMA1 Rabbit Polyclonal Antibody
Synonyms:   NUMA; NMP-22
UNIPROT ID:   Q14980 (Gene Accession – NP_006176 )
Background:    This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human NUMA1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 222374(NUMA1 Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 222374(Anti-NUMA1 Antibody) at dilution 1/50.
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