Email: info@neweastbio.com   |  Call: 6109452007

OCLN Rabbit pAb

Anti-OCLN Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216693

   Size:   100 μl

In Stock

            Product Description          
Cat.#:   S216693
Product Name:   Anti-OCLN Rabbit Polyclonal Antibody
Synonyms:   BLCPMG; PTORCH1; PPP1R115
UNIPROT ID:   Q16625 (Gene Accession – BC029886 )
Background:    This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Immunogen:    Fusion protein of human OCLN
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216693(OCLN Antibody) at a dilution of 1/70(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 216693(Anti-OCLN Antibody) at dilution 1/70.
          Publications