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OMG Rabbit pAb

Anti-OMG Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220770

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220770
Product Name:   Anti-OMG Rabbit Polyclonal Antibody
Synonyms:   OMGP
UNIPROT ID:   P23515 (Gene Accession – NP_002535 )
Background:    Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells; from dorsal root ganglion explants in which growth cone collapse was observed; from rat retinal ganglion neurons; and from NG108 and PC-12 cells.
Immunogen:    Synthetic peptide of human OMG
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220770(OMG Antibody) at a dilution of 1/30(Nucleus or Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220770(Anti-OMG Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220770(Anti-OMG Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261986(Anti-OMG Antibody) at dilution 1/30.
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