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ORAI1(L2) Rabbit pAb

Anti-ORAI1(L2) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213833

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213833
Product Name:   Anti-ORAI1(L2) Rabbit Polyclonal Antibody
Synonyms:   IMD9; TAM2; ORAT1; CRACM1; TMEM142A
UNIPROT ID:   Q96D31 (Gene Accession – NP_116179 )
Background:    The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
Immunogen:    Synthetic peptide of human ORAI1(L2)
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 213833(ORAI1(L2) Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 213833(Anti-ORAI1(Anti-L2) Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 213833(Anti-ORAI1(Anti-L2) Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D160923(Anti-ORAI1(Anti-L2) Antibody) at dilution 1/25.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human ovarian cancer tissue lysate;
Primary antibody: 213833(ORAI1(L2) Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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