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OVOL2 Rabbit pAb

Anti-OVOL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218858

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218858
Product Name:   Anti-OVOL2 Rabbit Polyclonal Antibody
Synonyms:   CHED; CHED1; CHED2; PPCD1; ZNF339; EUROIMAGE566589
UNIPROT ID:   Q9BRP0 (Gene Accession – BC006148 )
Background:    This gene encodes a member of the evolutionarily conserved ovo-like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N- and C-terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion, impaired vascularization, and heart anomalies. In humans, allelic variants of this gene have been associated with posterior polymorphous corneal dystrophy.
Immunogen:    Fusion protein of human OVOL2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 30-150;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Stem Cells, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218858(OVOL2 Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218858(Anti-OVOL2 Antibody) at dilution 1/50.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: Human cerebella tissue, Human cerebrum tissue, Human skin tissue, NIH/3T3 cell, SKOV3 cell lysates;
Primary antibody: 218858(OVOL2 Antibody) at dilution 1/350;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 seconds
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