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P2RY1 Rabbit pAb

Anti-P2RY1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219959

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219959
Product Name:   Anti-P2RY1 Rabbit Polyclonal Antibody
Synonyms:   P2Y1
UNIPROT ID:   P47900 (Gene Accession – NP_002554 )
Background:    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Immunogen:    Synthetic peptide of human P2RY1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219959(P2RY1 Antibody) at a dilution of 1/40(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 219959(Anti-P2RY1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 219959(Anti-P2RY1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with synthetic peptide and then with D260682(Anti-P2RY1 Antibody) at dilution 1/40.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: A549 cells, mouse liver tissue;
Primary antibody: 219959(P2RY1 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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