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p53 Rabbit mAb

Anti-p53 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262658

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262658
Product Name:   Anti-p53 Rabbit Monoclonal Antibody
Synonyms:   TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
UNIPROT ID:   P04637
Background:    Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
Immunogen:    Recombinant protein of human p53
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-6A7
MW:    Calculated MW: 44 kDa; Observed MW: 53 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Hypoxia Signal Transductionyyyyy Hypoxia-Inhibition
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of p53 (green) in MCF-7 using p53 antibody,and DAPI(blue)

Western blot analysis of p53 in Jurkat lysates using p53 antibody.
          Publications