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PAFAH1B3 Rabbit pAb

Anti-PAFAH1B3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219276

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219276
Product Name:   Anti-PAFAH1B3 Rabbit Polyclonal Antibody
Synonyms:   PAFAHG
UNIPROT ID:   Q15102 (Gene Accession – BC003016 )
Background:    This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B comple,x which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
Immunogen:    Fusion protein of human PAFAH1B3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219276(PAFAH1B3 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219276(Anti-PAFAH1B3 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 219276(Anti-PAFAH1B3 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D226181(Anti-PAFAH1B3 Antibody) at dilution 1/70.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane: Human fetal brain tissue lysate;
Primary antibody: 219276(PAFAH1B3 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 5 seconds
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