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PARP1 Rabbit pAb

Anti-PARP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220165

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220165
Product Name:   Anti-PARP1 Rabbit Polyclonal Antibody
Synonyms:   PARP; PARS; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; Poly-PARP
UNIPROT ID:   P09874 (Gene Accession – NP_001609.2 )
Background:    This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Immunogen:    Synthetic peptide of human PARP1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using 220165(PARP1 Antibody) at a dilution of 1/40(Nucleus).

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using 220165(Anti-PARP1 Antibody) at a dilution of 1/40.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Hela, K562 and Jurkat cell lysates;
Primary antibody: 220165(PARP1 Antibody) at dilution 1/350;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 second
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