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PCLAF Rabbit pAb

Anti-PCLAF Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219186

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219186
Product Name:   Anti-PCLAF Rabbit Polyclonal Antibody
Synonyms:   L5; PAF; OEATC; PAF15; OEATC1; p15PAF; NS5ATP9; OEATC-1; p15/PAF; KIAA0101; p15(PAF)
UNIPROT ID:   Q15004 (Gene Accession – BC005832 )
Background:    PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
Immunogen:    Fusion protein of human PCLAF
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 219186(PCLAF Antibody) at a dilution of 1/50(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 219186(Anti-PCLAF Antibody) at dilution 1/50.
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