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PDCD1 Rabbit pAb

Anti-PDCD1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213932

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213932
Product Name:   Anti-PDCD1 Rabbit Polyclonal Antibody
Synonyms:   PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
UNIPROT ID:   Q15116 (Gene Accession – NP_005009 )
Background:    Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Immunogen:    Synthetic peptide of human PDCD1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology, Immunology, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using 213932(PDCD1 Antibody) at a dilution of 1/50(Cell membrane).
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