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PDCD10 Rabbit pAb

Anti-PDCD10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216719

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216719
Product Name:   Anti-PDCD10 Rabbit Polyclonal Antibody
Synonyms:   CCM3; TFAR15
UNIPROT ID:   Q9BUL8 (Gene Accession – BC002506 )
Background:    This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen:    Fusion protein of human PDCD10
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Neuroscience, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216719(PDCD10 Antibody) at a dilution of 1/140(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216719(Anti-PDCD10 Antibody) at dilution 1/140.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: HepG2, K562, 231 cell lysates;
Primary antibody: 216719(PDCD10 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 90 seconds
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