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PDCD2 Rabbit pAb

Anti-PDCD2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220168

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220168
Product Name:   Anti-PDCD2 Rabbit Polyclonal Antibody
Synonyms:   RP8, ZMYND7
UNIPROT ID:   Q16342 (Gene Accession – NP_002589 )
Background:    This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.
Immunogen:    Synthetic peptide of human PDCD2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 220168(PDCD2 Antibody) at a dilution of 1/10(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 220168(Anti-PDCD2 Antibody) at dilution 1/10.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 220168(Anti-PDCD2 Antibody) at a dilution of 1/10.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D261075(Anti-PDCD2 Antibody) at dilution 1/10.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: Hela cells;
Primary antibody: 220168(PDCD2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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