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PDCD6 Rabbit pAb

Anti-PDCD6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216716

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216716
Product Name:   Anti-PDCD6 Rabbit Polyclonal Antibody
Synonyms:   ALG2; ALG-2; PEF1B
UNIPROT ID:   O75340 (Gene Accession – BC012384 )
Background:    This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.
Immunogen:    Fusion protein of human PDCD6
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 216716(PDCD6 Antibody) at a dilution of 1/80(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 216716(Anti-PDCD6 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 216716(Anti-PDCD6 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D221113(Anti-PDCD6 Antibody) at dilution 1/80.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-7: Mouse fetal liver tissue, Mouse lung tissue, K562, HepG2, 293T, A549, Hela cell lysates;
Primary antibody: 216716(PDCD6 Antibody) at dilution 1/1350;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 seconds
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