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PDE4D Rabbit pAb

Anti-PDE4D Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216721

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216721
Product Name:   Anti-PDE4D Rabbit Polyclonal Antibody
Synonyms:   DPDE3; PDE43; STRK1; ACRDYS2; HSPDE4D; PDE4DN2
UNIPROT ID:   Q08499 (Gene Accession – BC008390 )
Background:    This gene encodes one of four mammalian counterparts to the fruit fly ‘dunce’ gene. The encoded protein has 3′,5′-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Immunogen:    Fusion protein of human PDE4D
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 216721(PDE4D Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the fusion protein and then with 216721(Anti-PDE4D Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216721(Anti-PDE4D Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D221118(Anti-PDE4D Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: Human bladder carcinoma tissue, Human brain malignant glioma tissue, A172 cells, human fetal brain tissue, hela cells;
Primary antibody: 216721(PDE4D Antibody) at dilution 1/450;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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