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Perforin Rabbit pAb

Anti-Perforin Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225020

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225020
Product Name:   Anti-Perforin Rabbit pAb
Synonyms:   Perforin-1; P1; Cytolysin; Lymphocyte pore-forming protein; PFP
UNIPROT ID:   P14222
Background:    The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
Immunogen:    The antiserum was produced against synthesized peptide derived from the C-terminal region of human PRF1. AA range:451-500
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 61 kDa; Observed MW: 61 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human kidney using Perforin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Perforin in Hela lysates using Perforin antibody.

Immunohistochemistry analysis of paraffin-embedded Human kidney using Perforin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human spleen using Perforin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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