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Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Rabbit mAb

Anti-Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261715

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261715
Product Name:   Anti-Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Rabbit Monoclonal Antibody
Synonyms:   ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340
UNIPROT ID:   P04626
Background:    This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ErbB 2
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-6A8
MW:    Calculated MW: 138 kDa; Observed MW: 180 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of PhosohoErbB 2 (Tyr1248)/EGFR (Tyr1173) in Hela lysates using PhosohoErbB 2/EGFR (Tyr1248/Tyr1173) antibody.
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